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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP5
All Species:
26.97
Human Site:
Y249
Identified Species:
42.38
UniProt:
Q8N3R9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3R9
NP_071919.2
675
77294
Y249
V
Y
E
S
I
G
Q
Y
G
G
E
T
V
K
I
Chimpanzee
Pan troglodytes
XP_510014
764
85553
Y338
V
Y
E
S
I
G
Q
Y
G
G
E
T
V
K
I
Rhesus Macaque
Macaca mulatta
XP_001105724
674
77301
Y248
V
Y
E
S
I
G
Q
Y
G
G
E
T
V
K
I
Dog
Lupus familis
XP_547862
675
77214
Y249
V
Y
E
S
I
G
Q
Y
G
G
E
T
V
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB2
675
77211
Y249
V
Y
E
S
I
G
H
Y
G
G
E
T
V
K
I
Rat
Rattus norvegicus
Q5U2Y3
576
65604
F214
Q
S
Q
G
A
I
T
F
K
I
I
P
S
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505475
675
76860
Y249
V
Y
E
S
V
G
Q
Y
G
G
E
T
V
K
I
Chicken
Gallus gallus
Q5ZJ00
468
52501
R109
F
H
G
G
M
I
H
R
Q
G
S
L
H
V
G
Frog
Xenopus laevis
NP_001085267
675
76810
Y249
F
Y
E
N
I
G
L
Y
G
D
E
T
V
K
I
Zebra Danio
Brachydanio rerio
Q8JHF4
677
76390
W251
A
S
E
T
L
T
Q
W
G
G
E
T
V
K
I
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
H108
I
L
H
G
G
M
I
H
R
Q
G
S
L
H
E
Fruit Fly
Dros. melanogaster
Q24210
898
100893
G485
E
L
D
N
V
E
G
G
E
L
Q
H
V
T
R
Honey Bee
Apis mellifera
XP_393395
1033
115664
R588
T
S
S
W
R
G
S
R
V
V
D
N
I
K
I
Nematode Worm
Caenorhab. elegans
P54936
961
108794
S429
V
V
T
E
V
D
T
S
T
L
R
K
E
T
L
Sea Urchin
Strong. purpuratus
XP_784409
971
107892
D544
Q
D
I
D
L
P
E
D
G
E
E
S
V
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
97
98.2
N.A.
96.7
36.2
N.A.
93.7
25
86
77
25.7
26.7
34.7
24.1
34.7
Protein Similarity:
100
87.5
97.7
99.5
N.A.
98.6
54.9
N.A.
96.8
43.8
92.5
86.7
44.5
46.3
49.2
41.7
49.2
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
93.3
6.6
73.3
60
0
6.6
20
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
100
20
80
80
26.6
33.3
33.3
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
7
0
7
0
7
0
7
7
0
0
0
0
% D
% Glu:
7
0
54
7
0
7
7
0
7
7
60
0
7
0
7
% E
% Phe:
14
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
20
7
54
7
7
60
54
7
0
0
0
7
% G
% His:
0
7
7
0
0
0
14
7
0
0
0
7
7
7
0
% H
% Ile:
7
0
7
0
40
14
7
0
0
7
7
0
7
0
67
% I
% Lys:
0
0
0
0
0
0
0
0
7
0
0
7
0
67
7
% K
% Leu:
0
14
0
0
14
0
7
0
0
14
0
7
7
0
7
% L
% Met:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
14
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% P
% Gln:
14
0
7
0
0
0
40
0
7
7
7
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
14
7
0
7
0
0
0
7
% R
% Ser:
0
20
7
40
0
0
7
7
0
0
7
14
7
0
0
% S
% Thr:
7
0
7
7
0
7
14
0
7
0
0
54
0
20
0
% T
% Val:
47
7
0
0
20
0
0
0
7
7
0
0
67
7
0
% V
% Trp:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
47
0
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _